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Renal tubular necrosis, hypoglycemic coma, and thrombocytopenia may also Early symptoms following a potentially hepatotoxic overdose may include: hydrocodone nausea, vomiting, diaphoresis and general malaise .
Clinical and laboratory evidence of hepatic toxicity may not hydrocodone high how long does it last hydrocodone kidney disease hydrocodone with food hydrocodone be apparent until 48 to 72 hours post-ingestion .
In adults, hepatic toxicity has rarely been reported with acute overdoses of less than hydrocodone 10 grams and fatalities with less than 15 grams .
Treatment: A single or multiple overdose with hydrocodone and hydrocodone acetaminophen is a potentially lethal polydrug overdose, and consultation with a regional poison control center is recommended .
Immediate treatment includes support of cardiorespiratory function and measures to reduce drug hydrocodone 5 325 vs 10 325 hydrocodone hcl hydrocodone acetaminophen 5-325 what is it for absorption .
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