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If QTc interval is ⬎450 ms but ⬍500 ms, discuss potential risks and benefits with methadone york pa methadone xanax interaction methadone xanax overdose symptoms methadone nausea patients and monitor more frequently .
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Opioid Detoxification: Assess patient for signs of opioid methadone withdrawal (irritability, runny nose and eyes, abdominal cramps, body aches, sweating, loss of appetite, shivering, unusually large pupils, trouble sleeping, weakness, yawning) .
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