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It duphaston is indicated in all cases of endogenous progesterone deficiency .
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Dydrogesterone duphaston is completely metabolized .
The main metabolite of dydrogesterone duphaston is 20a-dihydrodydrogesterone (DHD) and is present in the urine predominantly as the glucuronic acid conjugate .
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duphaston After oral administration of dydrogesterone, plasma concentrations of DHD are substantially higher as compared to the parent drug .
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