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Pharmacotherapeutic group ATC Code: N02CA52 Ergotamine aborts attacks of migraine with or without aura by its specific vasotonic action cafergot on distended extracranial arteries .
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It displays moderate to high affinity for various serotonin receptor subtypes however its beneficial effect in migraine are primarily linked cafergot to agonist properties at 5-HT Regional changes to cerebral flows resulting from intracranial arterial vasodilatation accompany the migraine attack .
amoxil yellow teeth amoxil kidney infection amoxicillin qid amoxil prescribing information amoxil nz The mechanism seems to be related to a reduction in systemic levels of serotonin which, in turn, leads to the vasomotor changes observed .
Because of its direct vasoconstrictive cafergot effect on the smooth muscles of the dilated vessels, ergotamine aborts the migraine attack and vascular headaches .
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