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The prospective double-blind trial was performed in patients with stable acetaminophen davis acetaminophen dose liver acetaminophen level acetaminophen pain relief coronary disease who used paracetamol at the dose of 1 g three times a day for two weeks and the drug increased their blood pressure .
Its effect was similar to that acetaminophen exerted by diclofenac and ibuprofen .
Paracetamol due to its selective action towards COX-2 and similarly to coxibs but contrary to typical NSAIDs does acetaminophen not possess antiaggregatory properties .
The drug does not acetaminophen inhibit blood platelet action when taken at a single oral dose of 1000 mg .
However, acetaminophen clinical studies indicate antiaggregatory action of paracetamol in the case of parenteral administration in high doses (67, 68) .
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