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Mercaptopurine is an analogue of adenine, one of the bases required for nucleic acid biosynthesis, and of the purinethol purine base hypoxanthine .
Hence PURI-NETHOL acts as an antimetabolite and interferes with the purinethol de 50mg purinethol and alcohol purinethol farmaco ziek van puri nethol purinethol synthesis of nucleic acids in proliferating cells .
Its purinethol metabolites are also pharmacologically active .
Pharmacokinetics: Absorption of an oral dose of PURI-NETHOL is incomplete and variable averaging about purinethol 50% of the administered dose .
The half-life of mercaptopurine in the circulation is of the order purinethol misselijk purinethol image purinethol en zon purinethol rch purinethol bestellen of 90 minutes .
It is extensively metabolised and excreted via the kidneys and the active metabolites have a longer purinethol half-life than the parent drug .
7 and Treatment purinethol of acute leukaemia . Mercaptopurine has purinethol fiyati purinethol zon purinethol dove trovarlo purinethol kosten purinethol biverkningar pKa’s of 7 .
It is of value in remission induction and is particularly indicated for maintenance therapy in acute lymphoblastic leukaemia and acute myelogenous PURI-NETHOL is also purinethol used in the treatment of chronic granulocytic leukaemia .
PURI-NETHOL TABLETS – Product Information CONTRAINDICATIONS: Hypersensitivity to any component purinethol of the preparation .
In view of the seriousness of the indications there are no purinethol other absolute contraindications .
PURI-NETHOL IS AN ACTIVE CYTOTOXIC AGENT FOR USE ONLY UNDER THE DIRECTION OF PHYSICIANS purinethol EXPERIENCED IN THE ADMINISTRATION OF SUCH Immunisation using a live organism vaccine has the potential to cause infection in immunocompromised hosts .
Therefore, immunisations purinethol with live organism vaccines are not Co-administration of ribavirin and PURI-NETHOL is not advised .
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