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In animal reproduction studies, there were no adverse developmental effects with oral administration of rosuvastatin during organogenesis at systemic exposures equivalent to a maximum recommended human dose (MRHD) of 40 mg/day in rats or crestor rabbits (based on AUC and body surface area, respectively) . Because HMG-CoA reductase inhibitors decrease cholesterol synthesis and possibly the synthesis of crestor other biologically active substances derived from cholesterol, CRESTOR may cause fetal harm when administered to pregnant women . CRESTOR is crestor contraindicated for use in pregnant women since safety in pregnant women has not been established and there is no apparent benefit to therapy with CRESTOR during pregnancy . CRESTOR should crestor be discontinued as soon as pregnancy is recognized [see CONTRAINDICATIONS] . Limited published data on the use of rosuvastatin crestor missed dose crestor vs generic rosuvastatin crestor weakness best time to take crestor 5mg are insufficient to determine a drug-associated risk of major congenital malformations or miscarriage . In rats can crestor cause memory problems crestor muscle pain does crestor cause constipation crestor r and rabbits, decreased pup/fetal survival occurred at 12 times and equivalent, respectively, to the MRHD of 40 mg/day [see Data] .
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