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Naltrexone did naltrexone not exhibit clastogenicity in an in vivo mouse micronucleus assay .
Naltrexone (100 mg/kg/day [600 mg/m?/day] naltrexone PO; 16 times the recommended therapeutic dose, based on body surface area) caused a significant increase in pseudopregnancy in the rat .
A decrease in the pregnancy where to buy naltrexone in toronto buy naltrexone buy low dose naltrexone in uk buy nodict rate of mated female rats also occurred .
There was no naltrexone effect on male fertility at this dose level .
The relevance of these observations to human naltrexone fertility is not known .
Teratogenic Effects – Category C Naltrexone has been shown to increase the incidence of early fetal loss when given to rats at doses ? 30 mg/kg/day (180 mg/m?/day; 5 times the recommended therapeutic dose, based on body surface area) and to rabbits at naltrexone oral doses ? 60 mg/kg/day (720 mg/m?/day; 18 times the recommended therapeutic dose, based on body surface area) .
There was no evidence of teratogenicity when naltrexone was administered orally to rats and where to buy naltrexone in canada buy naltrexone online cheap buy naltrexone online uk buy rabbits during the period of major organogenesis at doses up to 200 mg/kg/day (32 and 65 times the recommended therapeutic dose, respectively, based on body surface area) .
Rats do not form appreciable quantities of the major human metabolite, 6-?-naltrexol; therefore, the potential reproductive toxicity of the metabolite in rats is not buy naltrexone india buy cheap naltrexone buy naltrexone india buy naltrexone online usa can you buy known .
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