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Superiority of mirtazapine over placebo was also found for certain remeron factors of the HDRS, including anxiety/somatization factor and sleep disturbance factor .
The mean mirtazapine dose for patients who completed these 4 studies remeron ranged from 21 to 32 mg/day .
remeron A fifth study of similar design utilized a higher dose (up to 50 mg) per day and also showed effectiveness .
In a longer-term study, remeron patients meeting (DSM-IV) criteria for major depressive disorder who had responded during an initial 8 to 12 weeks of acute treatment on REMERON were randomized to continuation of REMERON or placebo for up to 40 weeks of observation for relapse .
Response during the open phase was defined as having achieved a HAM-D 17 total score of ? 8 and a CGI-Improvement score of 1 or 2 at 2 consecutive visits beginning with week 6 of the 8 to 12 weeks in remeron the open-label phase of the study .
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