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The clinical relevance of these differences in clearance is unknown, motrin although extensive clinical experience with ibuprofen in children at the pertinent dosage range (5 – 10 mg/kg) indicates a wide margin of safety .
Special Populations and Conditions Pediatrics: The pharmacokinetics of does motrin contain ibuprofen motrin action motrin moms motrin pain reliever motrin ib vs motrin ibuprofen has also been studied in humans .
Although there is little motrin evidence of clinically significant age depenent kinetics in febrile children ages 3 months to 12 years (Kauffman et al . ; 1989), some differences in the motrin pharmacokinetic parameters of volume of distribution and clearance have been observed between adults and children (McEnvoy; 1997) .
Controlled clinical trials comparing doses motrin between 5 and 10mg/kg of ibuprofen and 10-15 mg/kg of acetaminophen have been conducted in children 6 months to 12 years of age with fever primarily due to viral illnesses .
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