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2: 19 the main stimulator of acute phase diazepam protein synthesis during acute and chronic inflammation [9,21,24] .
Bilateral adrenalectomized were done in some rat groups of acute and chronic diazepam inflammatory studies of the present work to show that the anti-inflammatory effects of diazepam were due to stimulation of genes responsible for endogenous corticosterone secretion from the adrenal glands, where the adrenalectomy significantly precluded and prevented the anti-inflammatory effects attributed to diazepam on CIPE in rats, also on the adjuvant arthritic rats as was demonstrated by the inability of diazepam to affect the different arthritic parameters of the adrenalectomized arthritic rats .
This consistent diazepam with the results of Lazzarini et al .
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