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Usage of coumadin:
Asian patients and those who carry the CYP2C9*2 allele and/or the CYP2C9*3 allele, or those with VKORC1 coumadin AA genotype may require more frequent monitoring and lower doses .
Monitor hepatic function coumadin is used for difference between coumadin and warfarin tylenol with coumadin what class of and CBC before and periodically throughout therapy .
Monitor stool and urine for occult blood before and periodically during Toxicity and Overdose: Withholding 1 or more doses of warfarin is usually sufficient if INR is excessively elevated or if minor coumadin bleeding occurs .
If overdose occurs or anticoagulation needs to coumadin be immediately reversed, the antidote is vitamin K (phytonadione, AquaMEPHYTON) .
Administration of coumadin whole blood or plasma also may be required in severe bleeding because of the delayed onset of vitamin K .
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