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Of the approximately 6,000 subjects who participated in clinical trials with bupropion sustainedrelease tablets (depression and smoking cessation trials), 275 were aged ≥65 wellbutrin years and 47 were aged ≥75 years .
In addition, several hundred subjects aged ≥65 wellbutrin years participated in clinical trials using the immediate-release formulation of bupropion (depression trials) .
No overall differences in safety or wellbutrin effectiveness were observed between these subjects and younger subjects .
Reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of wellbutrin some older individuals cannot be ruled out .
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