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The half-life of lamotrigine is affected by lamictal other concomitant medications [see Clinical Pharmacology (12 .
LAMICTAL Added to Drugs Known lamictal to Induce or Inhibit Glucuronidation Because lamotrigine is metabolized predominantly by glucuronic acid conjugation, drugs that are known to induce or inhibit glucuronidation may affect the apparent clearance of lamotrigine .
Drugs that induce glucuronidation include carbamazepine, phenytoin, phenobarbital, primidone, rifampin, estrogen-containing lamictal depression buy lamictal online lamictal canada lamictal medication lamictal canada lamictal oral contraceptives, and the protease inhibitors lopinavir/ritonavir and atazanavir/ritonavir .
Valproate inhibits lamictal glucuronidation .
For dosing lamictal considerations for LAMICTAL in patients on estrogen-containing contraceptives and atazanavir/ritonavir, see below and Table 13 .
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