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Patients treated topamax with TOPAMAX� experienced mean percent reductions in body weight that were dose-dependent .
This topamax change was not seen in the placebo group .
Mean changes of 0%, -2%, -3%, and -4% were seen for the placebo group, TOPAMAX� 50, 100, and 200 mg groups, topamax respectively .
(N=445) % TOPAMAX� Dosage (mg/day) In five, randomized, double-blind, placebo-controlled, parallel topamax group migraine prophylaxis clinical trials, most of the adverse reactions with TOPAMAX� were mild or moderate in severity .
Most does topamax cause diarrhea topamax weight what is topamax used for in depression topamax warnings adverse reactions occurred more frequently during the titration period than during the maintenance period .
Among adverse reactions with onset topamax during titration, approximately half persisted into the maintenance period .
In four, fixed-dose, double-blind migraine prophylaxis clinical topamax for depression reviews highest dose of topamax topamax memory drugs similar to topamax trials in TOPAMAX�-treated adolescent patients, the most commonly observed adverse reactions associated with the use of 100 mg of TOPAMAX� that were seen at an incidence higher ( ? 5%) than in the placebo group were : paresthesia, upper respiratory tract infection, anorexia, and abdominal pain (see Table 12) .
Table 12 shows adverse reactions from the adolescent pivotal trial (Study 3 demonstrating the efficacy of TOPAMAX�; [see Clinical Studies]) in which there were 103 adolescent patients who were treated with placebo or topamax 50 mg or 100 mg of TOPAMAX� and three predominantly adult trials in which there were 49 adolescent patients (12 to 17 years) who were treated with placebo or 50 mg, 100 mg or 200 mg of TOPAMAX� .
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