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Tapentadol IR (50, 100 and 200 mg) was compared tapentadol who ladder nucynta patent expiration tapentadol online pharmacy tapentadol bcs class with hydromorphone IR (4, 8 and 16 mg) .
Hydromorphone was selected because it is a µ-opioid analgesic under international control in accordance with schedule I of tapentadol the UN Single Convention on Narcotic Drugs and has similar pharmacokinetic properties to tapentadol .
The dosage selection was based on equi-analgesic potency conversion factors for hydromorphone, morphine and tapentadol in various animal tapentadol models .
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